Environmental Lead Exposure and Progressive Renal Insufficiency

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چکیده

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منابع مشابه

Renal effects of environmental and occupational lead exposure.

Environmental and industrial lead exposures continue to pose major public health problems in children and in adults. Acute exposure to high concentrations of lead can result in proximal tubular damage with characteristic histologic features and manifested by glycosuria and aminoaciduria. Chronic occupational exposure to lead, or consumption of illicit alcohol adulterated with lead, has also bee...

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Low-level environmental exposure to lead and progressive chronic kidney diseases.

PURPOSE To determine whether low-normal body lead burden (BLB) accelerates progressive renal insufficiency in nondiabetic patients with chronic kidney diseases (CKD). METHODS One hundred eight CKD patients (serum creatinine between 1.5 and 2.9 mg/dL) with low-normal BLB (<80 microg) and no lead exposure history were observed for 24 months. Following the observation, 32 patients with low-norma...

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Environmental and occupational exposure to lead.

OBJECTIVE To determine the status of environmental and occupational lead exposure in selected areas in Nairobi, Kenya. DESIGN Cross sectional study. SETTING Kariobangi North, Babadogo, Waithaka and Pumwani for assessment of environmental exposure to lead (Pb) and Ziwani Jua Kali works for assessment of occupational lead exposure. Olkalou in Nyandarua District was the covariate study area. ...

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Environmental Lead Exposure Accelerates Progressive Diabetic Nephropathy in Type II Diabetic Patients

Whether environmental lead exposure has a long-term effect on progressive diabetic nephropathy in type II diabetic patients remains unclear. A total of 107 type II diabetic patients with stage 3 diabetic nephropathy (estimated glomerular filtration rate (eGFR) range, 30-60 mL/min/1.73 m(2)) with normal body lead burden (BLB) (<600  μ g/72 hr in EDTA mobilization tests) and no history of exposur...

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Environmental lead exposure increases micronuclei in children.

The objective of this pilot study was to investigate the contribution of environmental exposures to lead in the development of cytogenetic damage detected as the frequency of micronuclei (MN) in children. The other aim was to apply the MN assay in combination with fluorescence in situ hybridization (FISH) using a pan-centromeric chromosome probe to elucidate the formation mechanism of induced M...

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ژورنال

عنوان ژورنال: Archives of Internal Medicine

سال: 2001

ISSN: 0003-9926

DOI: 10.1001/archinte.161.2.264